Movement is a characteristic of life. Substances must be circulated throughout the human body. They must enter cells to influence cellular metabolism. This movement is influenced by natural tendencies that may be augmented by physiological processes.







OSMOSIS





Osmosis is the diffusion of water across a membrane



Given the physical properties of water it is crucial that the cell--the basic unit of life, have the ability to easily receive or release water. As previously stated, the plasma membrane, due to the many aquaporins embedded within it, ensure that water can easily move across it. Therefore, water easily diffuses across the plasma membrane, However, the environment in which the water exists controls how and in what direction water diffuses.



Osmosis Rules


Osmosis occurs when the concentration of water differs on either side of the membrane.


In osmosis, the concentration of water is determined by the concentration of non-permeable solutes in the water. As the concentration of non-permeable solute increases the concentration of water decreases.





Applying the Rules





Cells exist in a watery environment


Many substances may be "dissolved" in the water.


Some of those substances are impermeable to the cell--meaning they cannot cross the plasma membrane


These impermeable solutes are able to "get in between" the water molecules and push them a little away from each other, thereby decreasing the concentration (not the volume) of the water.


Diffusion is the tendencies of molecules to move from a higher concentration to a lower concentration.


Since these impermeable molecules cannot enter the cell and water freely diffuses across the membrane the concentration of water changes outside of the cell, but the concentration inside remains the same (because those solutes cannot enter the cell).


There is now a difference in concentration of water outside of the cell versus inside of the cell.


Osmosis is the diffusion of water across a membrane.


Because there is now a lower concentration of water outside the cell as compared to inside of the cell, water diffuses from the inside of the cell into the extracellular space and due to the loss of water the cell may shrivel or crenate.


A solution that has an increased concentration of non-permeable solutes as compared to the cell is called a hypertonic solution.


A solution that has a decreased concentration of non-permeable solutes as compared to the cell is called a hypotonic solution.


This solution has an opposite effect on the water molecules, allowing them to become more concentrated as compared to inside of the cell.


Now based on the created concentration gradient, water will diffuse from the extracellular space into the cell, causing the cell to swell due to the increased water content.


In an isotonic solution the concentration of non-permeable solutes inside and outside of the cell are the same. Therefore water freely diffuses in a balanced manner with no demonstrable change in the cell shape or size.


Tonicity is the ability of a solution to change the shape or tone of a cell by altering its internal water content.






Cells are typically composed of 70% water. The fluid of the cell is called cytosol.





Cytosol is a gelatinous mixture of water and chemicals







Cytoplasm = Cytosol + Organelles


Organelles are the physiological “machines” of the cell that are embedded within the cytosol. They are the “little organs” that synthesize chemicals, manufacture other organelles, and mediate physiological reactions.

Organelles include:

nucleus

nucleolus

ribosome

vesicle

mitochondrion

lysosome

centriole

endoplasmic reticulum

golgi apparatus